Page 64 - MDA MIDEC 2024 Programme Book

ORAL PRESENTATION ABSTRACTS

P022 Name of Presenter: Wan Aeisyah Binti Wan Ahmed, Universiti Sains Malaysia
Title of Presentation: Oral Midazolam Sedation Efficacy in Paediatric Dental Patients with
8-6-4-2 Fasting or Light Meal Fasting Protocol

Abstract
Wan Aeisyah WA 1,*, Norsamsu Arni S 1, Zuliani M 1, Wan Muhamad Amir WA 1, Ruhaya H 1, Suki I 2
1 School of Dental Sciences, Universiti Sains Malaysia
2 Department of Anaesthesiology & Intensive Care, Hospital Universiti Sains Malaysia

Introduction: Fasting protocol is one of the important checklists prior to sedation, however, the pre-
operative fasting guidelines for conscious sedation vary to this day. There is limited evidence on the effects
of these different fasting protocols to the efficacy of oral sedation procedure.
Objective: The aim of this study is to assess the efficacy of oral midazolam (OM) sedation in different
fasting protocols in paediatric dental patients.
Methodology: 40 patients aged 3 to 17 years participated in this interventional study. They were randomly
assigned into two groups, which include the 8-6-4-2 fasting group and light meal group. The OM dosage
used was 0.5mg per kilogram bodyweight, with maximum dosage of 10mg. Evaluation was done on the
sedation onset and duration, adverse effects and treatment outcome using the overall Houpt Behavioural
Rating Scale.
Results: Duration of sedation for light meal group was longer (median= 46 minutes; IQR= 20 minutes)
compared to fasting group (median= 43 minutes; IQR= 19 minutes). However, there was no significant
difference in between the groups (p = 0.313). There was also no significant difference in the onset of
sedation in both groups (p = 0.067), however a pattern demonstrated that fasted patients take shorter
time for sedation onset (median= 20 minutes; IQR= 13 minutes) compared to light meal group (median=
36 minutes; IQR= 24 minutes). No adverse effects were observed in both groups. The Mann-Whitney U
test results indicate that there is no statistically significant difference (p= 0.161) in treatment outcome for
both groups.
Conclusion: Majority of the patients have good treatment outcome irrespective of fasting protocols.
The study found no significant difference in the efficacy of OM sedation between fasting and light meal
groups, suggesting that larger sample sizes may be necessary to provide more relevant findings.

Key words: sedation, paediatric, midazolam, fasting

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