Page 48 - MDJ Volume 47 Number 2 ( Jul-Dec 2024)

Abstracts
hybrid ceramic restorations have an acceptable survival devices as viable treatment options to address maxillary
rate, however debonding was a common complication. hypoplasia and class III malocclusion in CLP patients.
PICN restorations have a statistically significant higher Further studies are recommended to confirm these results
survival rate than RNC restorations. and refine treatment protocols.
Keywords: Computer-aided design and computer-aided Keywords: Class III elastics, cleft lip, cleft lip and palate,
manufacturing, endodontically treated teeth, hybrid ceramics, facemask, maxillary protraction device
survival

P003 P004
Clinical Effectiveness of Different Types of Maxillary Supragingival Bacterial Microbiota around Dental
Protraction Devices in Cleft Patient: A Systematic Implants and the Adjacent Tooth in Patients with a
Review and Meta-analysis History of Periodontitis
1
Nicholas Sim Choo Wee , A. M. Anis Rageh , S. Eshamsul ,
1
2
2
1
M. M. Ashwini , A. N. Mohamad Arif , R. Ahmad Hashridz 3
M. H. Norul Husna , S. Syarida Hasnur 1
1
1 Department of Paediatric Dentistry Unit, School of Dental Sciences,
Universiti Sains Malaysia Health Campus, Kubang Kerian, Kelantan, Malaysia, 1 Department of Restorative Dentistry, Faculty of Dentistry, Universiti Malaya,
2
2 Department of Biostatistics Unit, School of Dental Sciences, Universiti Sains Kuala Lumpur, Malaysia, Department of Medical Microbiology, Faculty of
Malaysia Health Campus, Kubang Kerian, Kelantan, Malaysia, Department of Medicine, Universiti Malaya, Kuala Lumpur, Malaysia
3
Orthodontics Unit, School of Dental Sciences, Universiti Sains Malaysia Health Objectives: The aim of this study was to investigate a
Campus, Kubang Kerian, Kelantan, Malaysia
causal link between the oral microbiota dysbiosis and
Introduction: Maxillary hypoplasia is a common challenge the risk of peri-implantitis in patients with a history of
in patients with cleft lip and palate (CLP), significantly periodontitis. Materials and Methods: Subjects with a
impacting facial aesthetics and function. Adolescents with history of periodontitis (Test) and periodontally healthy
this condition often require maxillary protraction therapy subjects (Control) were recruited to receive either of
to improve maxillary growth and correct malocclusion. two types of dental implants with different surface
Objective: This study aims to evaluate and compare characteristics: sandblasted, large grit and acid-etched
the clinical effectiveness of facemask with mini plates (SLA) or precision dimension laser-treated (PDL).
(FM-MP) and class III elastics with mandibular and Periodontal clinical measurements were recorded at
maxillary mini plates (C3-IE) in adolescents with CLP. baseline (V1), 3 months after implant placement (V4),
Methodology: A systematic review and meta-analysis at zirconia crown placement (V6) and 3 months after
were conducted following PRISMA guidelines. Five zirconia crown placement (V8). Supragingival bacterial
databases such as Scopus, Web of Science, PUBMED/ microbiota was studied using Illumina MiSeq sequencing.
Embase, Google Scholar and Cochrane Library were Results: Supragingival microbial community on SLA
searched for relevant studies from 2012 to 2024. Inclusion implants in the test group significantly differed to the
criteria encompassed prospective and retrospective control group at V8 (p < 0.05). After three months of
studies focused on maxillary protraction devices in CLP zirconia crown restoration (V6 to V8), a longitudinal
patients. The quality of included studies was assessed shift of the supragingival bacterial microbiome displaying
using the Newcastle Ottawa Scale (NOS) and GRADE microbial dysbiosis occurred on the SLA implants (p <
system. Data from five eligible studies were analyzed, 0.05) and the adjacent teeth (p < 0.05) among test patients.
with cephalometric measurements compared between Supragingival bacterial microbiome on PDL implants and
intervention and control groups using a random-effects the respective adjacent tooth did not differ significantly
inverse-variance model. Results: The meta-analysis between test and control groups from V6 to V8 (p >
revealed significant improvements in maxillary protrusion 0.05). Co-occurrence network in the test group of SLA
and correction of class III malocclusion post-treatment. implants at V8 and the adjacent tooth displayed increased
The FM-MP subgroup showed more pronounced changes disease-associated bacteria and reduced health-associated
in SNA, 2.14 degrees (95% CI: 0.97–3.31, p-value=0.003), bacteria. Health-associated bacteria were dominant in
ANB (improved 1.75 degrees), and overjet compared to the control group of SLA implants at V8. Conclusion:
the C3-IE subgroup. However, no significant differences The surface characteristics and prosthetic component of
were observed in the vertical dimension alterations or dental implants could be considered as important risk
mandibular rotation (p-value>0.05). The facemask with factors for the onset of microbial dysbiosis in patients
mini plates (FM-MP) was more effective in enhancing with a history of periodontitis. Dysbiosis of supragingival
overjet compared to class III elastics with bone anchors. microbiome in patients with a history of periodontitis
Conclusion: Maxillary protraction therapy is effective for may predispose dental implants to peri-implant mucositis
adolescents with CLP, with FM-MP showing superior or peri-implantitis, thus, a strict supportive periodontal
results in certain parameters compared to C3-IE. These care plan is imperative for these patients to prevent early
findings support the use of maxillary protraction onset of biological complications around dental implants.

74 Malaysian Dental Journal ¦ Volume 47 ¦ Issue 2 ¦ July-December 2024
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